In this fifth annual edition, drawn from Cerebrum’s highly regarded Web edition, some of the foremost experts in brain science present their research—and their take—on issues that capture the harmony as well as the discord in the complex and evolving relationship between neuroscience and society. Bruce S. McEwen, Ph.D., the Alfred E. Mirsky Professor and head of the Harold and Margaret Milliken Hatch Laboratory of Neuroendocrinology at the Rockefeller University, provides an insightful perspective on the impact of neuroscience on his career, and also the issues that especially resonated with him in the anthology’s articles.